PICK: Eagles underdogs at Bengals (-2.5) 🎥
Philly is an underdog for just the second time this season. Meanwhile, Cincy is just 3-4 with the three wins coming against the lowly Panthers, Giants and Browns.
PICK: Bills (-3) at Seahawks 🎥
Seattle is expected to be without wide receiver DK Metcalf and is just 2-4-1 ATS this season. Meanwhile, Buffalo is 1-0 ATS as a road favorite.
PICK: Cowboys at 49ers (-4.5) 🎥
Neither team is above .500 or leading their division. However, they are each one win behind the first place team.
Heisman: Oregon’s Gabriel passes Jeanty
After Boise State's Ashton Jeanty underdelivered based on his lofty standards, quarterbacks became the new Heisman Trophy betting favorite.
PICK: #12 Notre Dame (-14) vs. #24 Navy 🎥
The Midshipmen have covered all but one game, while all six games have gone over the total. But now Navy is in the underdog role, facing a Fighting Irish squad that has won five straight.
PICK: #5 Texas (-18) at #25 Vanderbilt 🎥
The Longhorns are coming off their first loss and now must face a Vandy team that has already sprung a couple upsets as a double-digit underdog.
PICK: #8 LSU at #14 Texas A&M 🎥
Both teams are riding six-game win streaks and undefeated in SEC play. Early money has arrived on the Tigers to make this a virtual coinflip game.
PICK: Pacers at Knicks (-5) 🎥
New York lost its season opener but host Indiana in a rematch of last year's playoff series that went seven games. New York was 29-8 ATS as a home favorite last season.
PICK: #17 Boise St. (-3.5) at UNLV 🎥
One-loss Mountain West teams square off on Friday night on national television, and the winner will get a leg up on the conference title and perhaps a playoff berth. The Rebels defense must find a way to contain Heisman betting favorite Ashton Jeanty.
Game 1 PICK: Yankees at Dodgers (-125)🎥
The World Series is expected to generate the largest betting ever for the Fall Classic. New York hands the ball to Gerrit Cole, as the Dodgers cashed the over in all six NLCS games.