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PICK: #5 Indiana at #2 Ohio St. (-10.5) 🎥

The undefeated Hoosiers have a chance to silence critics with this high-profile showdown at the Horseshoe. Curt Cignetti and the Hoosiers are 8-2 ATS this season can shake up the playoff mix with a strong performance.
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PICK: USC (-4.5) at UCLA 🎥

This rivalry game has postseason implications with the Trojans one win away from bowl-eligibility. Plus, the Bruins are two wins away with two remaining games.
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PICK: 49ers at Packers (-5.5) 🎥

San Francisco faces this virtual must-win game without quarterback Brock Purdy and defensive standout Joey Bosa. When the injury news surfaced, the point spread moved from two points to 5.5 points.