The undefeated Hoosiers have a chance to silence critics with this high-profile showdown at the Horseshoe. Curt Cignetti and the Hoosiers are 8-2 ATS this season can shake up the playoff mix with a strong performance.
The Gophers have won four of their last five games but did lose last weekend at Rutgers. Meanwhile, the Nittany Lions are 3-3 as a double-digit favorite this season.
This rivalry game has postseason implications with the Trojans one win away from bowl-eligibility. Plus, the Bruins are two wins away with two remaining games.
Kansas City suffered its first loss and now faces arguably the league's worst team. However, Carolina has won back-to-back games and is coming off a bye.
San Francisco faces this virtual must-win game without quarterback Brock Purdy and defensive standout Joey Bosa. When the injury news surfaced, the point spread moved from two points to 5.5 points.
Pittsburgh is 8-2 and eyeing a division title but has to travel on a short week against a division rival. However, the Steelers are undefeated with Russell Wilson at quarterback and are 8-2 ATS overall this season.
The Lakers have won six straight games and sit in third place in the Western Conference. Plus, Dalton Knecht is coming off a 37-point performance and his points prop is only 12.5.