PICK: Chargers at Steelers (-1.5) 🎥
In a battle of 2-0 teams, Pittsburgh welcomes Jim Harbaugh and the Bolt for their home opener. Plus, this total of 35.5 is the weekend's lowest.
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PICK: Panthers at Raiders (-5.5) 🎥
Former top overall draft pick Bryce Young has been benched so Andy Dalton will start for Carolina. Las Vegas is coming off a huge comeback win over Baltimore, ahead of its home opener.
Wide Receiver Harrison now Offensive Rookie co-favorite
After pedestrian starts by the rookie class' two marquee quarterbacks, wide receiver Marvin Harrison Jr. has surged up the betting board and is now a +250 Offensive Rookie of the Year co-favorite at DraftKings.
1-1 49ers remain NFC favorites
Despite falling to 1-1, the San Francisco 49ers remain +275 NFC favorites at DraftKings.
PICK: Bengals at Chiefs (-6) 🎥
Patrick Mahomes and two-time defending Kansas City host Cincinnati in a marquee matchup. Under Zac Taylor, the Bengals are only 1-10 in the first two weeks of the regular season.
PICK: Bears at Texans (-6.5) 🎥
In a matchup of young franchise quarterbacks on Sunday Night Football, CJ Stroud and Houston are a solid home favorite over Caleb Williams and Chicago.
PICK: Bills at Dolphins (-2.5) for TNF 🎥
Early money has shown on Miami and the under. What's the best way to play Thursday Night Football?
Harbaugh new Coach of Year favorite
After winning his Los Angeles Chargers debut, Jim Harbaugh is now the +750 betting favorite at DraftKings for the NFL Coach of the Year award.
Chiefs, Niners remain favorites
After home wins over contenders in their season openers, the Kansas City Chiefs and San Francisco 49ers remain conference favorites and even saw their odds lowered.
PICK: Jets at 49ers (-4) for MNF 🎥
After sitting out the entire preseason, Aaron Rodgers returns from his Achilles injury. San Francisco looks to overcome the jinx of the Super Bowl hangover.