Minnesota is 13-2 and defeated Green Bay at Lambeau Field earlier this season but is still just a short favorite. The Vikings can earn the NFC's top seed if they win their final two games.
The stakes are highest for Los Angeles, which can clinch the NFC West title and a playoff berth with a win. Arizona was the division favorite a few weeks ago but has since been eliminated from the postseason.
Exactly two weeks after it happened for the first time all NFL season, Thursday Night Football saw another longshot proposition bet of "no touchdowns scored" to cash with odds in the neighborhood of 120-to-1 odds.
Chicago has lost nine straight games but what version of Seattle will we see, after dropping two tough home games? The Seahawks are still technically alive for the playoffs.
In a matter of a week, Josh Allen's NFL MVP odds have shifted from -900 to -240 at DraftKings - not due to his play but because of Lamar Jackson's stellar play.
Kansas City is 14-1 and can clinch the AFC's top seed with a win. However, Pittsburgh is expected to welcome back wide receiver George Pickens and has typically thrived in the underdog role.
Baltimore is now a betting favorite to win the AFC South, and Lamar Jackson has even closed the gap in the MVP race. Meanwhile, the Texans have already clinched the AFC South.